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Recent MMWR reports (3–11) have indicated that bacteria account for 37 species reported as etiologic agents in LAIs; however, other microbes are often implicated.

Hepatitis B has been the most frequent laboratory-acquired viral infection, with a rate of 3.5–4.6 cases per 1000 workers, which is two to four times that of the general population.

Throughout these guidelines, quality laboratory science is reinforced by a common-sense approach to biosafety in day-to-day activities.



Work in a diagnostic laboratory entails safety considerations beyond the biological component; therefore, these guidelines also address a few of the more important day-to-day safety issues that affect laboratorians in settings where biological safety is a major focus. An estimated 500,000 persons in all professions work in human and animal diagnostic laboratories.

All functions of the human and animal diagnostic laboratory — microbiology, chemistry, hematology, and pathology with autopsy and necropsy guidance — are addressed.

A specific section for veterinary diagnostic laboratories addresses the veterinary issues not shared by other human laboratory departments.

Needle puncture, glass cuts, splash in eye, and bruises and cuts have the highest potential for infection from microbes.

In the hematology laboratory, the major causes of injuries are likely to be exposure to blood and body fluids; needle sticks, aerosols from centrifuge or removal of tube stoppers, tube breakage; or contaminated gloves (22).Warde Medical Laboratory, Ann Arbor, MI The material in this report originated in the National Center for Emerging and Zoonotic Infectious Diseases, Beth P. Telephone: 678-428-6319; Fax: 770-396-0955; E-mail: [email protected] Summary Prevention of injuries and occupational infections in U. BMBL-5, however, was not designed to address the day-to-day operations of diagnostic laboratories in human and animal medicine.


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